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Thursday, February 2, 2012

NIPER JEE 2011 paper

Niper 2011 Paper

1)Plantago…seed,root,bark
2)Aegle marmelose family…Rutaceae,malvaceae
3)competitive inhibitor….increase substate level
4)Short actin Drug….propofol,thiopental
5)Morphine discovered in…1904,1820
6)kaolin…hydrated Al silicate,hydrated Mg silicate
7)Controlled Drug delivery sym which is usd…HPMC,phalate,DCP
8)morphine…analgesic,anticonvulsant,both,none
9)Dry heat soln filling…..Dry heat sterilizatn,moist heat,aseptic fillin
10)D-glyceraldehyde configuration…S,R,RS
11)D-threose,D-erythrose,Lthreose related ques
12)erythrose and threose are???......distereoisomers,epimers,Enantiomers
13)Kaya skin clinic by company…ITC,
14)Indian institute of homeopathy??...Kolkata,jaipur,Bombay
15)preterm delivery vch drug use??..Atosiben,sulfoprostone,oxytocin
16)Psoralia obtaind from..Apigenin,Umbeliferone
17)Vch of following obtaind frm marine????...pralidoxime,heparin,both,none
18)Heparin ant..Ans protamine sulphate
19) 8 hrs…40km/hr…60 km/hr….ans 400
20)S is taller than a,a is taller than b lyk ques
21)witting reaction…phosprous
22)Cardinolide…butanone,batanedione,butanolides
23)Propranolol chemical name
24)Ehrlich reagent…P-dimethyl benzaldehyde
25)BCE;FGI:…
26)i-methyl benzoate..ii..phenyl acetate,,iii Acetophenone..IR range,,i=ii>iii,i>ii>iii
27)NH gives peak at..780,1100,3400
28)Stat phase nd mobile phase in RP chromatography..
29)Intracutaneous Max vol….0.01,0.1,0.2,1
30)BCCI memb
31)Fecl3+catechol colour….purple,red,green
32)Third generation sulphonamide usd in diabetis…Repaglinide,Glimipride,metformin,phenformin
33)Endothelial cell present in..Blood,lung,
34)Vch tissue has slowest equilibrium drug in blood…brain,fat,muscle,liver
35)platelets obtained from?? Ans megakaryotes
36)h2o nd D2O attack…Elimination,SN2,SN1
37)Walden inversion….SN1,SN2,E1,E2
38)Blood pH..7.4
39)Crystalline str related ques…
40)Vch method best suit to convert amorphous to crystalline….micronization,spray drying,any of above
41)emulsion measurement not by….electric charge,light scaterin,
42)DLVO theory…
43)microemulsion globule size…
44)beta galactosidase…SDS page…Band…2,1,,,,1,2….11….22…
45)PCR sequence
46)vch of following is not diuretic???..triamterine.indapamide,furosemide
47)Vch f followinnot active??...Allene,biphenyl.meso tartaric,None…
48)Gossypol…..not chiral,restricted rotation..
49)Eucalyptos oil ctn…geraneol,1-8 cineole,
50)AU..Bz..Cy….ans DX
51)20student height 120,10 student height 100…Avg height ans 105
52)Sania mirza….
53)German company take over.teva,sanofi,Pfizer..
54)book..fatima…
55)WOF used in tretmnt of diarrohea…erythromycin,domperidone,cisapride nd one new drug
56)cycloaddition..dial alder reactn
57)thinamerin dehydrogenation produce….antracene,naphthalene…
58)synthetic Ach better than natural Ach….due to slwer hydrolysis…
59)If increase dose f salbutamol,decrease actn by…downregulation,upregulatin…
60)vch is permeable..polystrene…
61)bond energy…..
62)Tymoleptics??
63)Max absorption from cell memb….ionizdform,unionized form…
64)WOf is not sede efeect of phenothiazine???
65)WOFis not hepatotoxic??..rifampicin,isoniazid,ethambuto,streptomycin
66)Inhibit Aminotranferase nd 30S….tetracycline,macrolide
67)Inhibitr f 50 s ….macrlide,tetracycline
68)synonym…Graphics
69)Pictorial
70)magnaminous
71)Rebate
72)WOF is antituberculosis drug???..Ethambutol..
73)Relience take over vch air li9ne?
74)Antinomycin D nd Rifampicin related confusin ques
76)DNA polymerase havin activity??...5 to 3,3 to 5,5 to 3 wth exonuclease,
77)SP angle…180
78)sesqueterpene havin isoprene unit,,,ans 3
79)In chewable tablet vch is usd?? Mannitol…
80Manitol used bz..Ans negativ heat f soln
81)CAP hydrolyze at pH….2.1..3.3…5.4….Ph indepedant
82)Anandamide….
83)Condensed tannin…Ans proanthocyanidin
84)Not sterilized by moist heat…taflon,polystyrene,polyethylene
85)leucopenia…decrese size of WBC,increase size f WBC
86)Estrogen higher level vch toxicity produce??...wieght loss,thrombophlebitis…
87)exothermic reaction Enrgy f product….Less,more
88)Father f pharmacognosy..hippocrates
89)benzyme    intermediate..
90)Organic cmpd+UV….electronic transition
91)Quantitativ estimation by..UV,IR,Mass,Nmr
92)St phase in cellulose chromatography…silica gel,water without OH.water with OH
94)PEG liposome….
95)WOF is wrong…aquacoat means enteric coatin
96)WOF is nt disacchrides….sucrose,maltose,lactose,glucopyranose
97)Glycolysis occur in…cytosol,mitochondia,nucleolus,nucleus
WOF occur in mitochondria..steroid synthesis,fat synthesis,
98)feed back inhibitin…
99)composite family nd one source belong to….terpene,alkaloids,glycoside,tannis
100)IR activity seen…change in dipole moment…
101)300 Mhz…c13 Nmr???.....75
102)Increse polarity..n to pi* transitn…bathochromic shift,hypsochromic shift…
103)WOF increase the QT interval…terfenadine nd other 3 option
104)WOF is action of diuretic..Urine formation,glucose formation,
105)Metabolite of hormone stored in…pancreas,adrenal medulla..
106)Bile is stored in…pancreas,gall blader,
107)Body Temp controlled by…hypothalamus…
108)Iregulation in moment due to…..cerebrum,cerebellu,
109)cardiac output/min calld……..cardiac cycle,cardiac output,force f contraction
110)most intense peak…Base peak…
111)Molar extinction coefficient Unit….
112)Acute amoebic dysentery vch drud used..metronidazole,chloroquine..
113)Flourouracil..ans inhibit thymidylate synthesis…
114)Folate deficiency by…methotraxate..
115)NSAIDS induced GITproblem handled by…mesoprostol
116)Insulin ph 5..hw to make longer actin insulin lyk dt ques…increase pH,lower pH
117)Longer actin penicillin…procain penicillin and other qption
118)WOF used as sorbent in tablet??.....MCC,silica,both,none
119)Acetylene value……ans lower than alkene
120)free radical stability….
121)free radical str…..ans planar
122)str of twisted boat…..
123)Tartaric acid inactive bz…..internal plane f symmetry..
124)WOF is prodrug..sulindac,sulphasalazine,aspirin
125)WOF is induced in allergy…IgE
126)WOF is participate in complement sym…IgG,IgM,IgE,IgA
127)Disinfectant fluid….ans Sch O
128)Vasaka leaf shape…ans lanceolate
129)glandular type,,,fracture….
130)agaropectin made up f….galactose nd uronic acid,glucose nd uronic acid
131)Arhenious Eqn related ques
132)Handersn hechalbatch…pH
133)Inflamation f brain…Ans meningitis…
134)GABA..increse cl level
135)Stainin..WOF is true abt gram positive stain
136)Eculle method 4 ans volatile oil
137)Vulcanizin agent…..S,SO2
138)IND full form
139)WOf is not product f dabur….meswak,glucose D,odomus
140)Colour added in vch step….syrup coatin
141)Interfacial tensn measured by..ostwald,brook field
142)vch is adultrant f saraca indica
143)tablet strength increser by ques lyk dat…..MCC,lactose
144)Mg stearate added in vch step of wet granulation…durin granulation,aft granulation
145)GC principle…adsorption,partition,both
146)Na salt f sachrin usd as….solublizin agent,bulkin gent,aweetnin agent
147) IV emulsion isotonic wth,,Nacl,KCL
148)IP h2O2….20%,80% lyk ques
149)Arsenic test apparatus use??…nessler cylinder
150)Doctor without border smthin lyk ques
151)subsidy definition..
152)dideoxy nucleotide differ frm deoxy nucleotide by…….less OH at 3rd carbon,More OH at 3rd carbon,lessH at 3rd carbon,more H at 3rd carbon
153)In m-RNA nucleotides are joinee by…phosphodiester bonds,glycosidic bond,hydrogen bond
154)Vd=X/C related ques,,ans 5 L
155)WOF is stron base….dimethyaniline,Pyrole,aniline,Pyridine
156)Enteric coated takes time in 0.1 N hcl…60,120,180,45
157)WOF used in efervesent tablet…citric acid+Na bicarbonate.
158)Wet granulation vch is nt used…Roler compactor,sigma blade mixer.
159)Contact angle related ques
160)Draves test,,ans weting angle
161)Cafeeine gives..ans murexide test
162)Meyer’s reagent….
163)Rhem rhizome use…..purgative,carminative,
164)Meltin f DNa increase..adeneni nd guanine,adenine nd thiamine,cytosine nd thiamine,
165)Topotecan…natural,synthetic,
166)H.pyroli induced hyperacidenia treated by???
167)clonidine….Antihypertensive,
168)Daughter cells divided in…Prophase,Anaphase,telophase
169)Company acquire vch hospital???..
170)Cyanide 540 UV gives colour……Blue,green,Red
171)PCI constituted by…central govt,state govt…
172)Carbopol….PVA,PVP
173)antioxidant wth reducing Prop??...tocopherol,hydroxyurea
174)Preservative used in ophthalmic??benzal konium Cl
175)Pharmaceutical Rotation by…molecule,crystal,both,None..
176)Increase lipase level indicate vch organ functn test…
177)USP apparatus 2…ans Paddle..
178)Streptomycin side effect….ans vestibular disturbance
179)Podophylotoxin…lignan dvt….
180)str of ketone treated wth LiAlH4